Monday, February 19, 2018

WE ARE MULTITUDES; MICROCHIMERISM: HOW PREGNANCY CHANGES THE MOTHER’S VERY DNA


Chimera greek mythology ile ilgili görsel sonucu

“Women are chimeras with gender material from both their parents and children. Where does that leave individual identity?”
By: Katherine Rowland
Level of Difficulty: ***
BEFORE YOU READ
·         What is Microchimerism | Lee Nelson https://www.youtube.com/watch?v=puYJp7SAGJc

·         Microchimerism and Diseases | Lee Nelson https://www.youtube.com/watch?v=VMuZRnuBaoI


QUESTIONS
1.       The fact that arthritis and lupus are not more prevalent in young women may indicate that there may be a connection / there may be no connection between…
2.       What precisely led Nelson to try and discover the long term effects of pregnancy?
3.       Read the paragraphs beginning “Evidence”, “Within weeks of conception” and that beginning “Far from drifting at random”. Which sentence would best summarize this section:
·         Children leave lasting traces of their time in the womb
·         Women unavoidably become microchimeras
·         Most women carry cells from more than one source
·         The give and take of cells during pregnancy needs to be considered
·         All of the above
·         Some of the above: please specify:
4.       Which sentence or phrase in the same section best summarizes the same three paragraphs?
5.       Microchimerism due to organ transplant is different from microchierism due to pregnancy in that………..
6.       The lack of rejection of cells exchanged during pregnancy probably has a social / evolutionary / familial / collective/ psychological basis.
7.       Where in the paragraph beginning “The phenomenon” would you place the following sentence: Cells exchanged during pregnancy, therefore, do not disappear; in fact they can remain intact throughout the lifetime of the host.
8.       The paragraph beginning “One of the most…” depicts a realistic/ romanticized/ literal/fundamental view of pregnancy and motherhood.
9.       Which sentence in the paragraph beginning “On one side…” best expresses the point the writer is trying to make?
10.   Women may in general be living longer than men because thanks to having kids, they have…………………
11.   We understand from Johnson’s research that if foetal cells caused disease they would / wouldn’t be ……………
12.   Both the cases of women who underwent thyroid surgery and the case of the woman with hepatitis C prove that ….
13.   What hypothesis was proved wrong by Amy Brody?
14.   Microchimeric cells act like an invading force from the beginning because…
15.   What conclusion can be drawn from the paragraph beginning “In other Words…”?
16.   What is the reason for the above?
17.   What is the underlying reason for the battle in the womb?
18.   The fact that microchimeric cells can extend birth intervals beyond the mother’s optimum time frame and the related 2010 study are proof that …
19.   According to Harvey Climan, the placenta acts deviously / deviantly / purposefully/ inherently because…
20.   What warning does the writer make in the conclusion? Why?
21.   Exchange of microchimeric cells between close relatives turns an individual into … (This question was contributed by my assistant Sinan Çakmak)
·         An isolated self with a dynamic inner world
·         A dynamic and ever-changing self
·         A collective self with shared motivations and affiliations
·         A multi-dimensional self with many underlying motivations

WRITING TASK
Use all the information you have acquired to describe how people become chimeras.
WE ARE MULTITUDES
MICROCHIMERISM: HOW PREGNANCY CHANGES THE MOTHER’S VERY DNA KEY AND TEACHERS’ NOTES
This completely fascinating text details the cell based exchanges between mothers and offspring and details the emergence of chimeras. It goes so far as to suggest that we are all chimeras to varying degrees and thus brings a whole new understanding to the concept of the self.  

1.       There may be no connection between female sex hormones and arthritis and lupus
2.       The fact that a female technician in a lab was found to contain male DNA a full year after the birth of her son
3.       Two and three
4.       With each successive conception, the mother’s reservoir of foreign material grows deeper and more complex, with…
5.       The genetic match between donor and recipient determines whether the body accepts or rejects the grafted tissue, or if it triggers disease
6.       Evolutionary
7.       At the end of the paragraph
8.       Romanticized
9.       But another body of research has found that foetal cells can protect the mother
10.   Greater immune surveillance and improved repair of damaged tissue
11.   Wouldn’t be everywhere
12.   There is definitely an association between the presence of foetal cells and improved disease status
13.   That microchimerism might preserve the health of mother and child, helping her survive childbirth and beyond as her offspring make their slow way to independence
14.   Because they act like a placenta beyond the womb, directing resources to the baby throughout gestation and after birth
15.   The womb might not be an enclave of rosy communion
16.   Conflict between the biology of the parent and the biology of the child
17.   For most genes, the foetus inherits two working copies one from the mother and one from the father. However, with imprinted genes, one of the copies is silenced…
18.   The foetus is a manipulative entity, conniving to direct the mother to its own advantage
19.   Deviously, because mothers marshal their best defensive tactics against offspring’s strategies to steal resources
20.   These analogies remain purely speculative, because there is no definitive proof that the microchimeric activity, commonly described as conflict, combat or colonization, reveals one entity pitted against the other
21.   The third


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